Malaria vaccines

There were an estimated 282 million malaria cases in 2024, an increase of 19 million cases compared to 2023. Approximately 95% of malaria cases occur in sub-Saharan Africa and mostly among African children under five years of age. ^{Go to footnote 11} Case incidence has remained largely unchanged since 2015.

In many endemic areas, malaria parasite transmission occurs throughout the year, often with seasonal variation; in areas of highly seasonal malaria, transmission is influenced largely by rainfall patterns and limited primarily to several months per year. Intensity is usually heterogeneous within a country: there may be areas with very high transmission, areas with variable transmission where sporadic epidemics affect all age groups, and areas with little or no malaria transmission. In areas of high malaria transmission, young children often experience multiple episodes of clinical malaria each year, even while utilizing available malaria control tools. ^{Go to footnote 22}