The SYSVAC registry includes a variety of systematic reviews, including living, rapid and umbrella reviews, allowing users to search for reviews using free text and keywords (e.g., disease/pathogen, population). Reviews in the registry have been assessed for quality, using the AMSTAR 2 (A MeaSurement Tool to Assess systematic Reviews 2) appraisal tool.
To include the most relevant systematic reviews in the field, registry staff regularly conduct searches of multiple databases, including Medline, Embase, and The Cochrane Library. For the registry’s December 2020 launch, priority was given to systematic reviews related to COVID-19. Systematic reviews covering more diseases/pathogens have been added since 2021.