Hexavalent vaccines

There are several schedule options with hexavalent vaccine. The schedule recommendation for hexavalent consists of 3 primary doses, starting as early as 6 weeks of age, with a minimum interval of 4 weeks between doses. 
Many countries are following a pentavalent schedule of 3 primary doses at 6, 10 and 14 weeks. In this case, the pentavalent vaccine can be substituted by the hexavalent vaccine at the same age. 
Countries that are currently following other pentavalent schedule options, can continue to maintain their schedules if they switch to hexavalent vaccine. Some schedules include, but are not limited to, primary doses given at 8, 12 and 16 weeks (equal to 2, 3 and 4 months of age) or, 8, 16 and 24 weeks (equal to 2, 4 and 6 months of age). In these cases, pentavalent vaccine can be substituted by the hexavalent vaccine at the same age. ^{Go to footnote 11, Go to footnote 22} . For hexavalent vaccines, a 3-dose schedule is adequate when initiated at ≥6 weeks of age and with a minimum of 4 weeks interval between doses. ^{Go to footnote 33}