Serogroup or serotype coverage by vaccines considered (for serogroup- or serotype-specific vaccines)

All vaccines cover >70% of serotypes which were circulating between 1980 and 2007 (before wider PCV use). 
10-valent Synflorix ® (GSK) and PCV13-Biomanguinhos covering serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23,
10-valent Pneumosil ® (SII) covering serotypes 1, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F and 23F
13-valent Prevenar-13 ® (Pfizer), PCV13-Sinergium, Weuphoria ® (Walvax), Beijing Minhai and Pneumotex ® (Nanolek) covering serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F
14-valent Pneumobevax ® (Biological E) covering serotypes 1, 3, 4, 5, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, 33F
15-valent Vaxneuvance ® (Merck/MSD) covering serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, 33F
20-valent Prevenar-20 ® (Pfizer) covering serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 23F, 8, 10A, 11A, 12F, 15B/C, 22F, 33
Cross-protection has been observed against serotype 6A for Synflorix® and against serotype 6C for Prevenar-13 ®.  Go to footnote 1

Sources
  • Go back to footnote reference 1

    World Health Organization (2025). Pneumococcal conjugate vaccines in infants and children under 5 years of age: WHO position paper – September 2025.

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