Vaccine Evidence Compendium

TCV vaccines

Logistics (feasibility)

Cold chain volume required per vaccine dose (in cm3)

Cold-chain volume varies by product and presentation. In secondary packaging, volumes are 14.45 cm³/dose for the Typbar-TCV single-dose vial and 2.9 cm³/dose for its 5-dose vial; 14.7 cm³/dose for the TYPHIBEV single-dose vial and 2.9 cm³/dose for its 5-dose vial; 2.62 cm³/dose for ZyVac TCV; and 3.05 cm³/dose for SKYTyphoid Multi Inj.

For specific product characteristics, see the comparison table.

Sources

  • World Health Organization (2026). WHO Prequalification of Medical Products: Typbar-TCV (single-dose and 5-dose presentations), TYPHIBEV® (single-dose and 5-dose presentations), ZyVac® TCV and SKYTyphoid Multi Inj. (https://extranet.who.int/prequal/vaccines/p/typbar-tcv; https://extranet.who.int/prequal/vaccines/p/typbar-tcv-0; https://extranet.who.int/prequal/vaccines/p/typhibevr; https://extranet.who.int/prequal/vaccines/p/typhibevr-0; https://extranet.who.int/prequal/vaccines/p/zyvacr-tcv; https://extranet.who.int/prequal/vaccines/p/skytyphoid-multi-inj, accessed 26 July 2026).

  • For specific product characteristics, see the comparison table.

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