Economic Evidence Supplementary Appendix to the Recommendations for Public Health Programs on the Use of Pneumococcal Vaccines in Children, Including the Use of 15-Valent and 20-Valent Conjugate Vaccines

A systematic review and de novo model-based economic evaluation were used as economic evidence to support decision-making for the use of 15-valent (Pneu-C-15) and 20-valent (PneuC-20) pneumococcal conjugate vaccines in the pediatric population. Each component is described below.