Service delivery (feasibility)
Measles-containing vaccines are administered in a 2-dose schedule to ensure immunity among individuals who do not respond to the first dose. In countries with ongoing measles transmission, the first dose is recommended at nine months of age and the second at 15–18 months. In countries with low transmission, the first dose may be administered at 12 months, with the second dose given according to the national schedule. The minimum interval between doses is four weeks.Go to footnote 1
Due to the high response rate, a single dose of rubella-containing-vaccine is sufficient for long lasting protection. A second dose is often given due to programmatic reasons and co-administration with measles, which has proven to be safe. Vaccination is recommended from nine months and can also be administered to older age groups.Go to footnote 2
Mumps-containing-vaccines are typically administered in a 2-dose schedule, co-administered as MMR or MMRV. Dose schedules are dependent on the national epidemiological and vaccine programme policy. The first dose is given at 9 – 12 months of age and the second dose administered during the second year of life or at school entry. The minimum interval between doses is four weeks.Go to footnote 2 Routine administration of a third dose is only considered during outbreaks in populations at increased risk.Go to footnote 3
Please consult the relevant position papers for varicella antigen.
- Go back to footnote reference 1
World Health Organization. Measles vaccines: WHO position paper – April 2017. Wkly Epidemiol Rec. 2017;92(17):205–27. (https://www.who.int/publications/i/item/who-wer9217-205-227, accessed 1 August 2026).
- Go back to footnote reference 2
World Health Organization. Rubella vaccines: WHO position paper – July 2020. Wkly Epidemiol Rec. 2020;95(27):306–324. (https://www.who.int/publications/i/item/WHO-WER9527, accessed 1 August 2026).
- Go back to footnote reference 3
World Health Organization. Strategic Advisory Group of Experts on Immunization (SAGE) Yellow Book: September 2023. Geneva: World Health Organization; 2023. (https://terrance.who.int/mediacentre/data/sage/SAGE_eYB_Sept2023.pdf, accessed 7 August 2026)