This standard operating procedure (SOP) describes the methodological concepts and steps used by the German Standing Committee on Vaccinations (STIKO) and serves as guidance for STIKO in the development of new vaccination recommendations. If there is a need for minor modifications to existing vaccination recommendations, the designated working group—in consultation with STIKO— decides which steps from this SOP are to be applied and to what extent. The present document reflects the current status of the methodological discussions within STIKO and the STIKO methods working group, and it will be updated if necessary.

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