Vaccination is considered to be the most effective way to prevent influenza. The health economic evaluation for seasonal influenza vaccine among elderly people has been studied for a long time in many countries yet a detailed review performance has not been introduced. The objective of the study is to review health economic evaluation studies on seasonal influenza vaccines targeted at elderly people. The search strategy was performed on databases including PubMed, Science Direct, and Cochrane Library. The inclusion criteria were designed to include scholarly articles and published peer-reviewed journal from 1992 until October 2015, with English as its publication language and use of primary or secondary data. Meanwhile, reviewed or methodological articles; the studies focusing on epidemiological aspects; lack of English full text, poster format, oral communications, or conference paper were excluded. In consider of the total 43 studies included, 14 of which were conducted in Europe and 29 others originated from extra-European countries, mainly from the United States. The number of published economic evaluations has gone up considerably between 2006 and 2015. The cost-effectiveness analysis (CEA) was often used to estimate economic impacts. The mixed outcome analysis was showed in most of several studies (37.2%) such as QALY and ICER combined. Costs were commonly computed with the societal perspective in 14 publications. The performance of sensitivity analysis took 86% of the publications. Under certain circumstances, such as in severe pandemics, influenza vaccination among elderly people is found to be cost saving with the higher efficacy and the lower vaccination cost. Copyright © 2017, Global Research Online. All rights reserved.
- Older adults
- Economic aspects
- Influenza
